Consulting
Process Development
Analytical Services
GMP Manufacturing
Facility Design & Process EngineeringAchieved GMP compliance through advanced optimisation, significantly enhancing yield and accelerating clinical readiness for a European biotech client’s AAV gene therapy.
Case Studies
Streamlining AAV Manufacturing for Clinical Scale-Up
The Challenge: Achieving GMP Compliance at Scale
A European biotech client developing pre-clinical AAV gene therapies for neurodegenerative diseases needed to scale-up and optimise their initial research process to achieve target dosage and GMP compliance for clinical application.
Our Approach
eXmoor Pharma conducted comprehensive process development, including cell line optimisation, media and filter screening, transfection optimisation, culture condition refinement, and anion exchange chromatography improvements through Design of Experiments (DoE) modelling.
Deliverables
The Outcome
Impact
The optimised, scalable manufacturing process significantly accelerated the client’s progression to clinical trials, supporting timely clinical development milestones.
Case Studies
See how eXmoor Pharma has helped biotech innovators scale their therapies with precision and efficiency.
Supporting Commercial Scale-up and Technology Transfer
Delivered strategic project management and seamless technology transfer, empowering TxCell’s commercial manufacturing scalability and operational success.
Translating iPSC Processes for Scalable GMP Manufacturing
Successfully converted adherent iPSC cultures to scalable suspension systems, enabling GMP-compliant clinical manufacturing and commercial scale-up readiness.
Let’s Accelerate Your Therapy Together
Whether you’re in early-stage development or scaling up for commercial production, eXmoor Pharma provides the expertise and flexibility you need. Partner with us to move your therapy forward with confidence.